Update, Oct 30th: Lady Gaga has now shared the official music video for “Disease” – check it out below!

Lady Gaga has returned with “Disease”, the explosive lead single from her forthcoming seventh album.

In a triumphant return to her dance-pop roots, “Disease” melds industrial basslines with dramatic beats, crafting a dark yet irresistible rhythm. With lyrics like, “Bring me your desire, I can cure your disease / If you were a sinner, I could make you believe,” Gaga invites listeners into a world of seduction and salvation—a captivating duality that’s central to the song’s infectious allure. She doubles down on this in the chorus, as her powerful voice demands, “Lay you down like one, two, three / Eyes roll back in ecstasy.”

Gaga teased “Disease” in a clever, cryptic way by updating a song title from each of her albums on Spotify, with lowercase letters forming an anagram of “Disease”—a move that had savvy fans buzzing with excitement.

To deepen the dark, seductive atmosphere of “Disease,” the song is paired with a new lyric video, drenched in a horror-inspired aesthetic. Lines from the song flash on a retro television screen, amplifying the eerie vibe and hinting at the intense visuals that may be featured throughout the new album.

With “Disease,” Gaga signals that her new album will be a theatrical exploration of desire, mystery, and raw emotional power—a journey her fans won’t want to miss.

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